加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

Caspase 8/CASP8 (p18)抗体图片
产品货号:
Z12739
中文名称:
Caspase 8/CASP8 (p18)抗体
英文名称:
Anti-Caspase 8/CASP8 (p18) Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Caspase 8/CASP8 (p18) Antibody
指标别名Apoptotic protease Mch 5;Casp 8;CASP8;Caspase 8;Caspase 8/p18;Caspase 8/p43/p18;caspase8;FADD like ICE;FLICE;ICE like apoptotic protease 5;MCH5
克隆性Polyclonal
检验物种human
应用范围WB,IHC
基因名称CASP8
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-8(p18)(257-277aa NNHNFAKAREKVPKLHSIRDR).
实际分子量18KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Caspase 8 is a caspase protein.It most likely acts upon caspase 3.This gene encodes a member of the cysteine-aspartic acid protease(caspase) family.The human CASP8 gene,whose product is also known as caspase 8 and FLICE,encodes an interleukin-1beta converting enzyme(ICE)-related cysteine protease that is activated by the engagement of several different death receptors.Caspase 8 is immediately recruited to the Fas receptor once it oligomerizes,and its protease activity is crucial for the apoptotic response generated by the resulting death-inducing signaling complex(DISC).This gene contains at least 11 exons spanning approximately 30kb on human chromosome band 2q33-34.This region of human chromosome 2 was previously reported as the location of the CASP10 gene,whose product is closely related to caspase 8.Caspase-8 deficiency in humans is compatible with normal development and shows that caspase-8 has a postnatal role in immune activation of naive lymphocytes.
Uniprot IDQ14790
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称caspase 8,apoptosis-related cysteine peptidase
蛋白名全称Caspase-8(CASP-8)
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:Caspase 8/CASP8 (p18)抗体Caspase 8抗体CASP8 (p18)多抗Anti-Caspase 8/CASP8 (p18) Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3